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Intraspinal injection of QHArt produces artemin in vivo. (a) 2 µl of QHArt or QHGFP containing 4 × 108 pfu was injected into thoracic spinal cord. Artemin RNA was detected at 1, 7, and 14 days after injection (QHArt). Control (C); injected with QHGFP (G). (b) GFRα3 RNA is expressed in uninjected thoracic spinal cord (reverse transcriptase-PCR). N = 4 rats per group. GFRα3, glial cell line–derived neurotrophic factor family receptor α3.
