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. 2009 Mar 31;17(7):1180–1186. doi: 10.1038/mt.2009.63

Figure 5.

Figure 5

Representative photomicrographs of lung tissues 7 days postintratracheal administration of LPEI/pLuc (N/P = 6) (a–c) or PEG-b-P[Asp(DET)]/pLuc (N/P = 80) (d–f). The terminal bronchiole and alveoli of the lungs administered with LPEI polyplex (a,b) and PEG-b-P[Asp(DET)] polyplex nanomicelle (d,e) are shown. The neutrophil infiltration is indicated with arrows in the photomicrographs with higher magnification (b,e). Each inset is the picture with higher magnification. The bronchus of the lungs administered with LPEI polyplex (c) and PEG-b-P[Asp(DET)] polyplex nanomicelle (f) are also shown. LPEI, linear poly(ethylenimine); PEG-b-P[Asp(DET)], PEG-b-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}.