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. 2009 May 26;17(8):1373–1380. doi: 10.1038/mt.2009.114

Figure 2.

Figure 2

Responses of 293T Lα cells transfected with the pCI-neoFCU1 and pCI-neoVP22(C14)FCU1 constructs. (a) Sensitivity of 293T Lα (WT), VF293T Lα (VP22FCU1), and F293T Lα (FCU1) cells to 5-fluorouracil (5-FU), cultured in the absence or presence of Dox [mismatch repair (MMR)-proficient and MMR-deficient conditions, respectively]. Survival was measured after 6 days of treatment using the vital dye resazurin. Error bars indicate the SD. (b) Sensitivity of 293T Lα (WT), VF293T Lα (VP22FCU1), and F293T Lα (FCU1) cells to 5-fluorocytosine (5-FC), cultured in the absence or presence of Dox. Survival was measured after 6 days using resazurin. Error bars indicate the SD. WT, wild type.