Fig. 17.

Ontogeny of mouse basolateral uptake transporter mRNA expression in kidneys. Tissues from C57BL/6 mice were obtained at −2, 0, 5, 10, 15, 22, 30, and 45 days. Day −2 represents gestational day 17. Male (♂) mRNA is shown on the left, whereas female (♀) mRNA is shown on the right side of each box. It is noteworthy that Oat1 and Oat3 mRNA expression was not quantified at day −2. Data are summarized from previous publications (Buist and Klaassen, 2004; Cheng et al., 2005a; Alnouti et al., 2006; Cheng and Klaassen, 2009).