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. Author manuscript; available in PMC: 2010 Mar 9.
Published in final edited form as: J Am Chem Soc. 2006 Oct 25;128(42):13676–13677. doi: 10.1021/ja065899k

Scheme 1.

Scheme 1

Potentiometric Detection of Sandwich Immunoassaya

a Conditions: (a) antigen addition, (b) capture of the gold nanoparticles labeled anti-mouse IgG antibody, (c) catalytic deposition of silver ions on the conjugated Au nanoparticles, (d) silver dissolution and potentiometric detection using a Ag+-selective electrode (ISE).