Fig. 7.

Effects of muscarinic agonist pretreatments in methylscopolamine substitution. Abscissae, methylscopolamine dose in mg/kg; “Sal” indicates saline. Ordinates, percentage of cocaine-appropriate responses (top); response rate in responses per second (bottom). Data are groups means ± S.E.M. Group sizes (Swiss-Webster mice): oxotremorine, n = 8; TBPB, n = 6. Exceptions to these group sizes are indicated when some mice failed to respond at a particular drug dose. *, p < 0.05; ***, p < 0.001 versus methylscopolamine alone.