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. 2010 Mar;332(3):1022–1031. doi: 10.1124/jpet.109.159194

Fig. 5.

Fig. 5.

Pharmacokinetics of 125I-anti-GPA scFv/PA fusion protein versus 125I-PA in mice. A, organ distribution of 125I-anti-GPA scFv/PA fusion protein versus 125I-PA after 1 h of circulation in mice. Inset, blood components distribution of 125I-anti-GPA scFv/PA fusion protein versus 125I-PA after 1 h of circulation in mice. B, blood clearance of 125I-anti-GPA scFv/PA fusion protein during 24 h of circulation after intravenous injection in mice. Inset, percentage of 125I-anti-GPA scFv/PA fusion protein recovered in plasma versus RBC pellet in blood obtained at the indicated times after intravenous injection of 125I-anti-GPA scFv/PA fusion protein in mice. (The number of animals in all experiments is 5 per group.) In each experiment the mean ± 1 S.E.M. is shown.