Fig. 8.

Resveratrol modulates DSS-induced CD4⁺ and CD8⁺ T cells during colitis. Splenic, MLN, and LP lymphocytes were isolated from the four groups of C57BL/6 mice (as shown in Fig. 1 legend) and stained for CD4⁺ and CD8⁺ T cells using flow cytometry. The numbers in the bottom right quadrant indicate the total percentage of CD4⁺ T cells (A); the numbers in the upper left quadrant indicate the total percentage of CD8⁺ T (A) cells. The number (mean of six samples ± S.E.M.) of total CD4⁺ T cells from MLN and LP in each group was counted (B). Data are shown from a representative of three independent experiments. Resveratrol was used at 100 mg/kg. Asterisks indicate statistically significance difference (P < 0.01) between DSS+vehicle and DSS+RES-treated mice.