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. 2010 Mar;332(3):1100–1106. doi: 10.1124/jpet.109.161232

Fig. 5.

Fig. 5.

a, relative expression of PLTP mRNA in human liver, primary hepatocytes, HepG2, and Huh7 cells. Gene expression was analyzed by TaqMan real-time polymerase chain reaction as described under Materials and Methods. The relative expression is presented relative to the expression level in liver. b, inhibition of apoB secretion by compound A and MTP inhibitor CP-346086 in Huh7 cells. c, dose-dependent inhibition of apoB secretion by compound A in HepG2 cells. HepG2 or Huh7 cells were treated with the compounds for 24 h, and medium was collected for apoB and transferrin measurement by ELISA. Data are the average of triplicates ± S.D.