Figure 1.

Amino acid sequence of Pin2 and its relationship with TRF1. (A) The predicted Pin2 peptide sequence is indicated in the one-letter code, with the arrow indicating the site at which the additional 20 amino acids are present in TRF1. Boxes with white letters from left to right indicate an acid (D/E)-rich domain, a D-like box, a bipartite nuclear localization signal and a Myb-type HTH DNA-binding domain. (B) Schematic presentation of the domain structure of the Pin2 and TRF1 proteins and sequence of the 20 amino acid insert in TRF1.