Table 1. Effects of the tested compounds on the growth of BAEC cells1.
Compound | IC50 (µM) |
1 (hyperforin DCHA) | 2.1±0.7 |
2 | 12.4±1.5* |
3 | 12.4±3.1* |
4 | 4.5±2.0* |
5 | 84.4±12.7* |
6 | 5.3±1.7* |
7 | 8.0±2.0* |
8 | 1.7±0.1 |
IC50 values were calculated from dose-response curves as the concentration of compound yielding a 50% of control cell survival. They are expressed as means±S.D. of three different experiments with quadruplicate samples in each.
*Mean values are significantly higher than that of hyperforin (p<0.05, according to a Student's paired sample test).