Table 2.
Lipid management drugs and their effects on lipid/lipoprotein
| Drug class | LDL | HDL | TG |
|---|---|---|---|
| HMG-CoA reductase inhibitors (statins)3 | Decrease 18%–55% | Increase 5%–15% | Decrease 7%–30% |
| Bile acid sequestrants3 | Decrease 15%–30% | Increase 3%–5% | No change or increase |
| Niacin (nicotinic acid)3 | Decrease 5%–25% | Increase 15%–35% | Decrease 20%–50% |
| Fibric acid derivatives3 | Decrease 5%–20%, may increase in patients with high TG | Increase 10%–20% | Decrease 20%–50% |
| Ezetimibe51 | Decrease about 18% | Increase about 1% | Decrease about 8% |
Abbreviations: LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglyceride.