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BCG does not induce changes in 5-HT
| WT | IFNγR−− | |||
|---|---|---|---|---|
| Saline | BCG | Saline | BCG | |
| 5-HT | 2.47 ± 0.11 | 2.51 ± 0.16 | 2.56 ± 0.011 | 2.49 ± 0.13 |
| 5-HIAA | 1.07 ± 0.07 | 1.19 ± 0.07 | 1.20 ± 0.06 | 1.15 ± 0.09 |
| 5-HIAA/5-HT | 435 ± 0.05 | 475 ± 0.02 | 474 ± 0.03 | 466 ± 0.04 |
Serotonin and its major metabolite 5-HIAA were measured by HPLC in brain tissue from WT or IFNγR−− mice treated with either saline or BCG. Data represent mean (micromoles per milligram of tissue) ± SEM; n = 3–9 mice per group.
