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(A) Low-intensity pulsed ultrasound stimulation (LIPUS) increased extracellular signal-regulated kinase-1/2 (ERK-1/2) expression at 14 days. ERK-1/2 expression was similar in the 7-day group compared with the 21-day group and compared with their respective sham groups. (B) LIPUS increased P-ERK-1/2 in the 7-day and 14-day groups. P-ERK-1/2 was similar in the 21-day group compared with its sham group. IB = immunoblotting; * = control group.
