Fig. 2.
Immunohistochemical analysis of IL-10 expression by GA-specific cells in brains of EAE-induced mice. (A–F) Perivascular infiltration in the thalamus. (G–I) Enlarged images of single cells in the thalamus. (L–N) Single cells in the cortex. (O–R) Nonoverlapping distribution of IL-10-expressing, GA-labeled cells and additional population of cells expressing IL-10 and GFAP in tissue surrounding the lateral ventricle. Controls demonstrate IL-10 expression in corresponding brain regions of an EAE-induced mouse (J) and a normal mouse (K). (Scale bar: A–C, 50 μm; D–F, 20 μm; G–I and L–N, 10 μm; J, K, and O–R, 100 μm.)