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. Author manuscript; available in PMC: 2010 Mar 9.
Published in final edited form as: Diabetologia. 2008 Apr 18;51(6):978–988. doi: 10.1007/s00125-008-1002-3

Table 1.

Measures of Body Weight and Adiposity in Alox5−/− and WT Mice

Females Males

Weight (g) Fat (g) % Body Fat Weight (g) Fat (g) % Body Fat
10 weeks
Alox5−/− 19.9 ± 0.3 2.5 ± 0.3 12.4 ± 1.2 a26.0 ± 2.3 a2.8 ± 0.2 a10.8 ± 0.5
WT 18.6 ± 0.1 2.0 ± 0.3 12.2 ± 1.3 23.8 ± 1.7 1.9 ± 0.4 7.9 ± 1.0
14 weeks
Alox5−/− a24.1 ± 0.4 a2.8 ± 0.8 a11.7 ± 1.4 a29.0 ± 1.6 a3.5 ± 0.2 a12.2 ± 0.2
WT 21.6 ± 0.3 2.0 ± 0.1 9.5 ± 0.5 26.4 ± 1.7 2.0 ± 0.4 7.5 ± 0.9
16 weeks
Alox5−/− a27.5 ± 0.2 a2.9 ± 0.6 a10.6 ± 0.24 a30.0 ± 1.7 a3.9 ± 0.4 a12.9 ± 0.5
WT 22.8 ± 0.1 2.0 ± 0.01 9.3 ± 0.2 26.4 ± 1.5 2.0 ± 0.1 7.6 ± 0.2
19 weeks
Alox5−/− a28.7 ± 0.1 a3.4 ± 0.4 a11.9 ± 1.3 a31.2 ± 1.9 a3.9 ± 0.5 a12.4 ± 1.2
WT 23.4 ± 0.2 2.0 ± 0.2 8.8 ± 0.9 27.5 ± 1.5 2.0 ± 0.2 7.3 ± 0.7

Note: Five mice of each genotype group were weighed at the indicated ages and adiposity was determined by NMR. Data are shown as mean ± SE and statistical comparisons were only made within each gender group.

a

P < 0.05 between Alox5−/− and WT mice.