Alignment of predicted amino acid sequence of E1 and E2 of HCV strain H77 (13), E1 and E2 derived from H77 and incorporated into the HCV genotype 1a pseudotype particle (10), E1 and E2 derived from HCV strain TN (genotype 1a) (19, 20), and E1 and E2 derived from HCV strain J (genotype 1b) and incorporated into the HCV genotype 1b pseudotype particle (11). Black, C′ end of core; blue, E1; brown, E2; bold, HVR1 of E2.