Table 1.
Summary of lipid profiles in rats fed a high cholesterol diet and treated with different concentrations of FPS.
| Control (n = 10) |
HC group (n = 10) |
FPS (224 mg/kg) (n = 10) |
FPS (448 mg/kg) (n = 10) |
FPS (869 mg/kg) (n = 10) |
P-value^ | |
|---|---|---|---|---|---|---|
| Cholesterol (mmol/L) | 1.33 ± 0.19 | 2.89 ± 0.48† | 2.20 ± 0.38†‡ | 1.91 ± 0.46‡ | 1.93 ± 0.37‡ | <0.001* |
| Triglyceride (mmol/L) | 0.79 ± 0.21 | 0.85 ± 0.33 | 0.88 ± 0.38 | 0.76 ± 0.36 | 0.87 ± 0.35 | 0.942 |
| LDL-C (mmol/L) | 0.79 ± 0.07 | 1.97 ± 0.46† | 1.20 ± 0.15†‡ | 1.13 ± 0.10‡ | 1.27 ± 0.21†‡ | <0.001* |
| HDL-C (mmol/L) | 1.11 ± 0.17 | 1.22 ± 0.27 | 1.19 ± 0.24 | 1.11 ± 0.26 | 1.15 ± 0.33 | 0.830 |
Data are presented as the mean ± standard deviation.
HC = high cholesterol; FPS = Polysaccharide from Fuzi; LDL = low-density lipoprotein; HDL = high-density lipoprotein.
^P-values are based on analysis of variance testing.
* Indicates an overall significant difference (P < 0.05).
† Indicates a statistically significant difference between the highlighted treatment group and the control group (P < 0.05).
‡Indicates a statistically significant difference between the highlighted treatment group and the HC group (P < 0.05).
Pair-wise multiple comparisons between groups were determined using Bonferroni's test with α = 0.007 adjustment.