Table 2.

Summary of hepatic HMG-CoA reductase and CYP7α-1 mRNA expression levels in rats fed a high cholesterol diet and treated with different concentrations of FPS.

mRNA levels	Control (n = 10)	HC group (n = 10)	FPS (n = 10)	P-value^
HMG-CoA reductase	1.29 ± 0.36	4.17 ± 1.83†	0.73 ± 0.39‡	<0.001*
CYP7α-1	0.78 ± 0.43	0.74 ± 0.49	4.08 ± 1.58†‡	<0.001*

Data are presented as the mean ± standard deviation.

HC = high cholesterol; FPS = Polysaccharide from Fuzi;

^P-values are based on analysis of variance testing.

* Indicates an overall significant difference (P < 0.05).

^† Indicates a statistically significant difference between the highlighted treatment group and the control group (P < 0.05).

^‡Indicates a statistically significant difference between the highlighted treatment group and the HC group (P < 0.05).

Pair-wise multiple comparisons between groups were determined using Bonferroni's test with α = 0.017 adjustment.