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. Author manuscript; available in PMC: 2011 Apr 25.

Published in final edited form as: Virology. 2010 Feb 18;400(1):93–103. doi: 10.1016/j.virol.2010.01.029

WNV titers did not differ substantially in mice inoculated with 10⁵ PFU of WNV^C6/36 or WNV^BHK except at the earliest time points. Mice were inoculated subcutaneously with 10⁵ PFU of WNV^C6/36 (●) or WNV^BHK () in the left rear footpad. Tissues were harvested at various times post-inoculation, and plaque assays were performed to determine the viral load in (A) serum, (B) ipsilateral footpad (inoculation site), (C) draining popliteal lymph node, and (D) spleen. Data from two independent experiments are shown. Solid lines indicate the geometric mean for each group of 6–12 mice. Dashed lines represent the limit of detection (LOD), and data points below the line are < LOD. Asterisks denote significant difference between groups (Mann-Whitney test: ** p <0.05; ***p <0.005).

Inline graphic — WNV titers did not differ substantially in mice inoculated with 10⁵ PFU of WNV^C6/36 or WNV^BHK except at the earliest time points. Mice were inoculated subcutaneously with 10⁵ PFU of WNV^C6/36 (●) or WNV^BHK () in the left rear footpad. Tissues were harvested at various times post-inoculation, and plaque assays were performed to determine the viral load in (A) serum, (B) ipsilateral footpad (inoculation site), (C) draining popliteal lymph node, and (D) spleen. Data from two independent experiments are shown. Solid lines indicate the geometric mean for each group of 6–12 mice. Dashed lines represent the limit of detection (LOD), and data points below the line are < LOD. Asterisks denote significant difference between groups (Mann-Whitney test: ** p <0.05; ***p <0.005).