Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2011 Apr 25.

Published in final edited form as: Virology. 2010 Feb 18;400(1):93–103. doi: 10.1016/j.virol.2010.01.029

Mice inoculated with WNV^C6/36 produced IFN-α/β earlier than mice inoculated with WNV^BHK. Mice were inoculated subcutaneously with (A) 10⁵ PFU of WNV^C6/36 (●) or WNV^BHK (), (B) 10 PFU of WNV^C6/36 (●) or WNV^BHK () or 10³ PFU of WNV^C6/36 (○) or WNV^BHK (□) in the left rear footpad. Sera were harvested at different times post-inoculation, and IFN bioassays were performed on L929 cell monolayer. Data from two independent experiments are shown. Solid lines indicate the geometric mean of 6 mice per group. Dashed lines represent the limit of detection (LOD), and data points below the line are < LOD. Asterisks show significant difference between groups (Mann-Whitney test: ** p <0.05).

Inline graphic — Mice inoculated with WNV^C6/36 produced IFN-α/β earlier than mice inoculated with WNV^BHK. Mice were inoculated subcutaneously with (A) 10⁵ PFU of WNV^C6/36 (●) or WNV^BHK (), (B) 10 PFU of WNV^C6/36 (●) or WNV^BHK () or 10³ PFU of WNV^C6/36 (○) or WNV^BHK (□) in the left rear footpad. Sera were harvested at different times post-inoculation, and IFN bioassays were performed on L929 cell monolayer. Data from two independent experiments are shown. Solid lines indicate the geometric mean of 6 mice per group. Dashed lines represent the limit of detection (LOD), and data points below the line are < LOD. Asterisks show significant difference between groups (Mann-Whitney test: ** p <0.05).