Table 1.
Amounts of Human Serum Albumin (HSA) Measured after Enrichment in Fresh and Archived Samples. (HSA-Cys34 adducts are represented by the amounts of HSA after enrichment via treatment with thiol-affinity resins).
| Subject or Pool | Type of HSA | Smoker | Gender | Race | HSA. (mg) | Adducts (mg/mg HSA)a |
|---|---|---|---|---|---|---|
| 1 | Fresh | No | M | A | 1.41 | 0.079 b |
| 1 | Fresh | No | M | A | 1.41 | 0.065 b |
| 1 | Fresh | No | M | A | 1.41 | 0.071 b |
| 1 | Fresh | No | M | A | 1.41 | 0.074 b |
| 1 | Fresh | No | M | A | 1.41 | 0.091 b |
| 2 | Archived | No | F | B | 0.262 | 0.357 |
| 2 | Archived | No | F | B | 0.262 | 0.295 |
| 3 | Archived | No | F | W | 0.212 | 0.304 |
| 3 | Archived | No | F | W | 0.212 | 0.278 |
| 4 | Archived | No | M | W | 0.214 | 0.331 |
| 4 | Archived | No | M | W | 0.214 | 0.346 |
| 5 | Archived | No | M | W | 0.184 | 0.460 |
| 5 | Archived | No | M | W | 0.184 | 0.419 |
| 6 | Archived | Yes | F | B | 0.274 | 0.296 |
| 7 | Archived | Yes | F | W | 0.264 | 0.259 |
| 7 | Archived | Yes | F | W | 0.264 | 0.315 |
| 8 | Archived | Yes | M | B | 0.261 | 0.305 |
| 8 | Archived | Yes | M | B | 0.261 | 0.321 |
| 9 | Archived | Yes | M | W | 0.208 | 0.237 |
Legend: M=male, F=female, A=Asian, B=black, W=white.
a
HSA measured after treatment with thiol-affinity resins.
b
Includes 0.047 mg IAA-HSA/mg HSA (positive control).