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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Pain. 2009 Nov 27;11(3):247–255. doi: 10.1016/j.jpain.2009.07.010

Table 1.

Effect of Neonatal Bladder Treatments on Measures of Nociception and Cystometric Measures

Measure Neonatal Zymosan Neonatal Anesthesia
Somatic Nociceptive Measures
N 7 8
Hindpaw Thermal Threshold (sec) 8.4 ± 0.5 8.2 ± 0.2
Hindpaw Mechanical Threshold (gm) 128.5 ± 7.6 129.7 ± 18.6
Visceral Nociceptive Measures
N 7 10
Abdominal Electromyographic Activity During Bladder Filling (Δ rectified mV from baseline) 270 ± 100* −70 ± 110
Transurethral Cystometric Measures
N 13 12
Micturition Volume Threshold (ml) 0.80 ± 0.09* 0.99 ± 0.01
Resting Pressure (mm Hg) 2.626± 0.362 2.568 ± 0.298
Transabdominal Cystometric Measures
N 5 5
Micturition Volume Threshold (ml) 0.150 ± 0.052* 0.488 ± 0.144
Resting Pressure (mm Hg) 8.935 ± 2.331 7.202 ± 1.895
Peak Pressure (mm Hg) 32 ± 1 31 ± 3

Values are Mean ± SEM

*

indicates statistically significant difference from Neonatal Anesthesia group with with p<0.05; Student's t-test and Mann-Whitney U tests