Figure 7. Intrahepatic injection of HSC into newborn IL2rγ^null strains.

Newborn mice were irradiated and injected via the IH route with CD34⁺ cells as described in Materials and Methods. Twelve to 16 weeks after HSC engraftment, the percentages of human CD45⁺, CD3⁺ and CD20⁺ cells in peripheral blood (A) and spleen (B) were determined by flow cytometry. The solid lines represent the median value for each group. The proportion of T cells and B cells is a percentage of the human CD45⁺ cell numbers. Each dot represents an individual animal.