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Effect of oxidized procyanidin fractions (FI-FV) on 3H-MPP+ apical uptake (respresented as %, considering control treatment as 100%) by Caco-2 cells and Caco-2 cells maintained with 25 mM glucose (HG Caco-2). Confluent Caco-2 monolayers were preincubated for 60 min with oxidized procyanidins and then incubated with 200 nM 3H-MPP+ for 5 min in the presence of etOh (control) or the tested compounds. each value represents the mean ± SEM (n = 3–27). *p < 0.05.
