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Representative images of hydronephrosis in Lean Control (LC) and Zucker diabetic fatty (ZDF) rats at 16 and 36 weeks of age. Kidneys were cut across the cross-sectional axis of the hillar region. Evidence of progression of morphologic changes is seen in both LC and ZDF kidneys from 16 to 36 weeks of age with hydronephrosis being more severe in the diabetic animals.
