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. 2010 Feb 19;107(7):114–121. doi: 10.3238/arztebl.2010.0114
abl: Abelson kinase (chromosome 9), part of Philadelphia translocation t(9;22) and therapy target structure for the tyrosine kinase inhibitors imatinib, nilotinib and dasatinib
AP: Accelerated phase of CML
BC: Blast crisis of CML
bcr-abl: Gene or protein product of Philadelphia translocation t(9; 22)
CCyR: Complete cytogenetic response (see Table 1 for definition)
CHR: Complete hematological response (see Table 1 for definition)
CML: Chronic myelogenous leukemia
CMR: Complete molecular response (see Table 1 for definition)
CP: Chronic phase of CML
IFN: Interferon alpha
MCyR: Major cytogenetic response (see Table 1 for definition)
MMR: Major molecular response (see Table 1 for definition)
PCyR: Partial cytogenetic response (see Table 1 for definition)
PDGFR: Platelet-derived growth factor receptor
PFS: Progression-free survival (no progression in AP/BC)
Ph+ ALL: Philadelphia chromosome-positive acute lymphatic leukemia
qRT-PCR: Quantitative real-time polymerase chain reaction