abl: |
Abelson kinase (chromosome 9), part of Philadelphia translocation t(9;22) and therapy target structure for the tyrosine kinase inhibitors imatinib, nilotinib and dasatinib |
AP: |
Accelerated phase of CML |
BC: |
Blast crisis of CML |
bcr-abl: |
Gene or protein product of Philadelphia translocation t(9; 22) |
CCyR: |
Complete cytogenetic response (see Table 1 for definition) |
CHR: |
Complete hematological response (see Table 1 for definition) |
CML: |
Chronic myelogenous leukemia |
CMR: |
Complete molecular response (see Table 1 for definition) |
CP: |
Chronic phase of CML |
IFN: |
Interferon alpha |
MCyR: |
Major cytogenetic response (see Table 1 for definition) |
MMR: |
Major molecular response (see Table 1 for definition) |
PCyR: |
Partial cytogenetic response (see Table 1 for definition) |
PDGFR: |
Platelet-derived growth factor receptor |
PFS: |
Progression-free survival (no progression in AP/BC) |
Ph+ ALL: |
Philadelphia chromosome-positive acute lymphatic leukemia |
qRT-PCR: |
Quantitative real-time polymerase chain reaction |