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. Author manuscript; available in PMC: 2010 Dec 14.
Published in final edited form as: Biochemistry. 2009 Dec 15;48(49):11724–11736. doi: 10.1021/bi900853v

Figure 4.

Figure 4

A. Far-UV CD of abatacept, B.Far-UV CD of CTLA-4, C. Near-UV CD of abatacept. All at 10 °C. D. Second derivative UV absorbance spectra overlapping at both pH’s at 20 ° C. Protein in 10 mM sodium phosphate buffer with 25 mM NaCl at pH 6 (dashed line or filled circles) and 7.5 (solid line or open circles)