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. 2003 Nov 17;100(24):14439–14444. doi: 10.1073/pnas.2435457100

Fig. 2.

Fig. 2.

Reduced tonic conductance in δ-/- mice. (A) Effects of GABAAR blockade on the holding current in two representative DGGCs from δ-/- mice (details as in Fig. 1 A). The tonic current is smaller than that seen in wild-type mice, and is not increased by 100 nM THDOC (see Fig. 1 A). (B) Tonic conductance in DGGCs from wild-type (filled bar) and δ-/- mice (open bars). Note the significant reduction in tonic conductance (asterisk), and the lack of effect of 100 nM THDOC, in δ-/- mice. (C) Averaged sIPSCs recorded in a DGGC from a δ-/- mouse, illustrating the effect of 100 nM THDOC. (D and E) Data from CGCs.