Fig. 1.
Schematic representations of the oxidative part of the hexose-monophosphate shunt and relevant sources of oxidative load (a) and of the simplified reaction network used in our analysis (b). Nonstandard abbreviations: Cat, catalase; G6P, glucose 6-phosphate; GL6P, gluconolactone 6-phosphate; Glc, glucose; GO6P, gluconate 6-phosphate; GO6PD, gluconate 6-phosphate dehydrogenase; GSSG, oxidized glutathione; GPx, glutathione peroxidase; GSR, glutathione reductase; HK, hexokinase; SOD, superoxide dismutase.