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. 2009 Dec 14;86(1):55–62. doi: 10.1093/cvr/cvp399

Figure 2.

Figure 2

C2-Cer (2 μM, 10 min) activated outwardly rectifying Cl− current in symmetrical Cl−. (A) Families of currents and (B) I–V relationships. C2-Cer-induced current reversed near 0 mV. (C) C2-Cer-induced current at 60 mV was 1.30 ± 0.35 pA/pF (n = 6, P < 0.01). Outward rectification in symmetrical Cl− and block by DCPIB (Figure 1) indicate C2-Cer activated ICl,swell.