Table 4.
Allele | Binders | Non-Binders | Total | DynaPredPOS | NetMHC | SVMHC | YKW | |
---|---|---|---|---|---|---|---|---|
(n) | (n) | (n) | AUC | AUC | AUC | AUC | ||
1 | A*0201 | 33 | 143 | 176 | 0.92 | 0.94 | 0.82 | 0.93 |
2 | A*0301 | 11 | 165 | 176 | 0.77 | 0.92 | 0.70 | 0.85 |
3 | A*1101 | 17 | 159 | 176 | 0.84 | 0.89 | 0.72 | 0.83 |
4 | A*2402 | 37 | 139 | 176 | 0.90 | 0.78 | 0.90 | 0.64 |
5 | B*0702 | 9 | 167 | 176 | 0.86 | 0.98 | 0.72 | 0.68 |
6 | B*0801 | 10 | 166 | 176 | 0.97 | 0.92 | 0.97 | 0.61 |
7 | B*1501 | 14 | 162 | 176 | 0.71 | 0.92 | 0.71 | 0.80 |
Average AUC | 0.85 | 0.90 | 0.79 | 0.76 |
A set of 176 novel peptides, generated and tested by Lin et al [15], were used to test the prediction accuracy of the four methods in this study. The average AUC for each method is included at the bottom of each column.