Figure 2. The position of the FVB.B6-Sicd1 congenic segment responsible for reduced susceptibility to seizure-induced cell death and the 5-Mb peak LOD.

The chromosome 18 region containing the Sicd1 QTL is a 12-Mb interval between D18Mit141 and D18Mit144. The peak LOD region (79–84 Mb) contains an estimated 12 known candidate genes that show human homology. Map distance is illustrated in megabase and all distances are from http://www.ensembl.org.