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. Author manuscript; available in PMC: 2010 Mar 10.
Published in final edited form as: Epilepsia. 2008 Jul 24;50(4):629–645. doi: 10.1111/j.1528-1167.2008.01725.x

Figure 5.

Figure 5

Decreased parvalbumin and neuropeptide Y neurons in the CA3 regions of NPN2 (−/−) mice. Forty-micron sections from NPN2 (+/+) (n = 9) or NPN2 (−/−) (n = 9) mice were subjected to immunocytochemistry using the GABA (panel A versus B), Parvalbumin (panel C versus D), neuropeptide Y (panel E versus F) antibodies. The number of GABA+ neurons was decreased by 63% in both subregions of CA3 (panel A versus B). Cell counts of Parv+ neurons in the CA3 region were decreased by 42% (panel C versus D, black arrows). There was a remarkable 71% decrease in NPY+ neurons in the CA3 region of (−/−) mice (panel E versus F).

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