Figure 1. Intravenous post-exposure MVA immunization provides better protection than intranasal immunization.

C57BL/6 mice were infected intranasally with 3×10⁴ TCID₅₀ of ECTV. Mice were left untreated or immunized after 2 (A), 3 (B) or 5 (C) days with 5×10⁷ TCID₅₀ of MVA either intravenously or intranasally. Note, in C no i.n. group was included. Survival was monitored for 32 days. The experiments were performed with 3–5 mice/group. Experiments for A were performed twice, for C once and B shows one exemplary experiment out of three.