Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Mar 11;5(3):e9655. doi: 10.1371/journal.pone.0009655

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Baran et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Diagrams of defects in axon extension and commissure outgrowth observed in newly hatched mutant worms (see Table 2). The morphology of the DD neurons in wild-type and mutant worms was visualized with the cytoplasmic axon markers P_unc-25GFP or P_flp-13GFP. Examples of axon defects in tubulin mutants: (B), (C) short regions (arrows) where axons fail to extend to their full length along the dorsal nerve cord of tba-1(ju89) worms; (D) a commissure branches prematurely and fails to reach the dorsal nerve cord in a tbb-1(gk207) mutant animal; (E) axon outgrowth or extension defects in all six DD neurons of a newly hatched L1 larvae. The DD6 commissure stalls prematurely (arrow), and the DD2 cell body is also displaced anterior. (F) abnormal commissure branch (arrow) in a tba-1(ju89) mutant. Scale bar 20 µM.