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. Author manuscript; available in PMC: 2011 Mar 15.
Published in final edited form as: Transplantation. 2010 Mar 15;89(5):500–508. doi: 10.1097/TP.0b013e3181c73c34

FIGURE 3. Morphological changes of lymphatics after transplantation (n=4 per time point).

FIGURE 3

(A) Lymphatic density in the inner myocardium (inner 2/3 of transverse heart section). Allograft inner lymphatic density decreased 38.6-fold at week 1 post-transplantation and recovered to 14.29% of the level in DA native hearts at 8 weeks post-transplantation. There was a significantly greater decrease in inner lymphatic density in allografts compared to isografts. αp=0.02. βp=0.02. (B) Lymphatic density in the outer myocardium and subepicardium (outer 1/3 of transverse heart section). No significant difference was seen among allografts, isografts and native hearts. (C) Lymphatic size in the inner myocardium (inner 2/3 of transverse heart section). Allografts and isografts had similar increase (2.3-fold) at 8 weeks post-transplantation when compared to native hearts (p=0.02). (D) Lymphatic size in the outer myocardium and subepicardium (outer 1/3 of transverse heart section). Allografts and isografts had similar increases in size and showed no significant difference throughout the post-transplantation course. Outer lymphatic size stayed at about 2.9 times that of native hearts at the time of transplantation from week 3 through week 8 after transplantation in isografts and allografts (εp=0.03).