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. Author manuscript; available in PMC: 2011 Feb 17.
Published in final edited form as: Adv Drug Deliv Rev. 2009 Nov 14;62(2):122–149. doi: 10.1016/j.addr.2009.10.004

Fig. 11.

Fig. 11

Multivalency effect in the biorecognition of HPMA copolymer–peptide–DOX conjugates. Inhibition of Raji B cell growth by exposure to HPMA copolymer–DOX (P (GFLG)–DOX) conjugate containing varying amount of targeting peptide, EDPGFFN-VEIPEF, per macromolecule. (A) Structure of conjugate; (B) inhibition of Raji B cell growth by P(GFLG)–DOX (no targeting peptide), P(GFLG)–DOX containing 1.9 mol% targeting peptide, and P(GFLG)–DOX containing 3.9 mol% targeting peptide. Adapted from [123].