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. Author manuscript; available in PMC: 2011 Feb 17.
Published in final edited form as: Adv Drug Deliv Rev. 2009 Nov 14;62(2):122–149. doi: 10.1016/j.addr.2009.10.004

Fig. 22.

Fig. 22

First synthesis and application of semitelechelic poly(HPMA) to modify surface of nanospheres. (A) Structure; (B) adsorption isotherms of IgG onto surface-modified P (MMA-MA-MAA) nanospheres in 1/15 M saline at 25 °C for 3 h. Each point represents the mean±SD (n=3); (C) body distribution profiles for unmodified and modified [14C]-P(MMA-MA-MAA) nanospheres in rats 24 h after i.v. administration and the correlation with Mn of ST-PHPMA. Each point represents the mean±SD (n=5) [191].