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. Author manuscript; available in PMC: 2011 Jan 28.
Published in final edited form as: J Med Chem. 2010 Jan 28;53(2):876–886. doi: 10.1021/jm900556s

Table 5.

Biodistribution of radioactivity in tissues (other than tumor and brain) of tumor-bearing Fischer rats following intravenous administration of (R)-[18F]8.

Tissue 15 min 30 min 60 min 120 min
Blood 0.41±0.03 0.32±0.04 0.24±0.08 0.14±0.04
Heart 0.55±0.14 0.23±0.02 0.24±0.08 0.22±0.01
Lung 0.79±0.28 0.36±0.02 0.38±0.19 0.25±0.06
Liver 0.60±0.12 0.61±0.11 0.52±0.07 0.40±0.09
Pancreas 2.25±1.16 2.72±0.62 3.41±0.48 3.39±0.79
Spleen 0.57±0.06 0.63±0.06 0.59±0.11 0.62±0.09
Kidney 9.22±1.26 8.91±1.32 4.44±0.89 2.45±1.10
Muscle 0.27±0.07 0.23±0.03 0.20±0.02 0.22±0.03
Bone 0.51±0.09 0.48±0.08 0.51±0.08 0.44±0.13
Testis 0.19±0.07 0.15±0.01 0.15±0.06 0.16±0.06

Values are reported as mean percent injected dose per gram tissue (%ID/g) ± standard deviation; n=5 at each time point.