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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Feb 16;19(3):746–754. doi: 10.1158/1055-9965.EPI-09-1085

Table 2.

Tests of Mediation Pathways*

Race → PCR Race → mediator Mediator → PCR controlling for race Race → PCR controlling for mediator Sobel statistic (P-value) % Effect
Hypothesized mediator = family history of cancer
Black −0.41 (−0.54 to −0.28) −0.62 (−0.90 to −0.34) 0.48 (0.39 to 0.57) −0.35 (−0.48 to −0.22) −3.99 (<0.001) 14.6
Hispanic −0.35 (−0.49 to −0.21) −1.06 (−1.39 to −0.73) 0.44 (0.35 to 0.53) −0.24 (−0.39 to −0.10) −5.29 (<0.001) 29.8
Asian −0.71 (−0.92 to −0.50) −1.79 (−2.36 to −1.22) 0.48 (0.38 to 0.57) −0.52 (−0.73 to −0.30) −5.34 (<0.00) 27.2

Hypothesized mediator = smoking status
Black −0.41 (−0.54 to −0.27) Ns
Hispanic −0.35 (−0.49 to −0.21) −0.43 (−0.72 to −0.14) 0.35 (0.26 to 0.44) −0.31 (−0.45 to −0.17) −2.77 (0.006) 10.4
Asian −0.71 (−0.92 to −0.50) −1.23 (−1.79 to −0.68) 0.38 (0.30 to 0.46) −0.61 (−0.82 to −0.41) −4.02 (<0.001) 13.4

Hypothesized mediator = belief that everything causes cancer
Black −0.41 (−0.54 to −0.27) −0.28 (−0.45 to −0.11) 0.15 (0.11 to 0.19) −0.37 (−0.50 to −0.24) −3.03 (0.002) 8.2
Hispanic −0.35 (−0.49 to −0.21) −0.38 (−0.55 to −0.21) 0.15 (0.11 to 0.20) −0.28 (−0.43 to −0.14) −3.66 (0.002) 17.9
Asian −0.71 (−0.92 to −0.50) −0.39 (−0.64 to −0.15) 0.18 (0.14 to 0.23) −0.62 (−0.81 to −0.43) −3.15 (0.002) 12.3
*

Untransformed coefficients and 95% confidence intervals for pathways that must be statistically significant to support mediation and results of Sobel Test of statistical significance for the mediating effects

PCR = perceived cancer risk

All models included age, marital status, gender, and education as covariates