Table 1.
GPCR name | Drosophila orthologs (ligands) | PG Expression | Functional features and characteristics |
BNGR-A15 | CG14484 [MIP/AST-B] (21) | No (20) | No response to PTSPs at up to 10−5 M |
BNGR-A14 | CG14593 | No (20) | No response to PTSPs at up to 10−5 M; BNGR-A15 paralog |
BNGR-B4 | No obvious ortholog | Yes (20) | No response to PTSPs, PTTH, BMS, or BRFas at up to 10−5 M |
BMSR | CG8985, CG13803 [DMS] (21, 22) | Yes (20) | No response to PTSPs; high and moderate response to BMS and BRFas, respectively (6, 7) |
SPR (PTSPR) | CG16752 [SP] (23) | Yes | High response to PTSPs |
DMS, dromyosuppressin. Expression analysis and functional characterizations were conducted in this study unless specifically referenced.