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Gene expression profile. Control or Mdr2−/− (KO) livers of 9-month-old mice that underwent PHx were analyzed by Affymetrix arrays. Functional analysis of the up-regulated genes on day 6 after PHx in control (A) or KO (B) mice. (C) Graph illustrating the fold change in gene expression of representative differentially regulated genes involved in DNA damage and repair between KO vs. control mice before PHx. The horizontal dashed line marks a fold change of 1 (no change).
