Figure 2.

Alizarin red S staining of the skeletons of newborn wild-type and transgenic mice. (A) Lateral view of skull, thoracic cage, and hindlimb; and frontal view of lumbar vertebra of a wild-type mouse (left), and a homozygous Tg-A (right) littermate; (so) supraoccipital bone, (st) sternum, (vt) lumbar vertebrae, (is) ischium, (pb) pubic bone, (tb) tibia. (B) Lateral view of forelimb (upper) and hindlimb (lower) of a wild-type mouse (left), and a homozygous Tg-B (right) littermate; (rd) radius, (il) ilium, (is) ischium, (pb) pubic bone, (mt) metatarsal bones, (tb) tibia.