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In situ hybridization with 35S-labeled type X collagen cRNA of decalcified tibiae from a 3-week-old Tg-A/PTHrP+/+ mouse (A) and a Tg-A/PTHrP−/− (B) littermate; both animals were homozygous for the transgene. The sections were stained with hematoxylin and eosin; the bright field view of the proximal epiphysis is shown.
