Table 2.
Adjusted odds ratios (ORs) with 95% confidence intervals (95% CIs) for dispensed osteoporosis drugs in 450,482 women and 280,623 men in Sweden, 2005
Bisphosphonates OR (95% CI) | Calcium + vitamin D supplements OR (95% CI) | Raloxifene OR (95% CI) | |
---|---|---|---|
Women | |||
Age (years) | |||
75–79 | Ref | Ref | Ref |
80–84 | 0.95 (0.93, 0.98) | 1.06 (1.04, 1.08) | 0.76 (0.67, 0.86) |
85–89 | 0.75 (0.72, 0.77) | 1.02 (1.00, 1.05) | 0.48 (0.40, 0.56) |
≥90 | 0.36 (0.34, 0.38) | 0.81 (0.78, 0.83) | 0.24 (0.18, 0.32) |
Type of residential area | |||
Rural | Ref | Ref | Ref |
Urban | 1.25 (1.21, 1.29) | 1.34 (1.31, 1.36) | 2.03 (1.76, 2.33) |
Number of other drugs | |||
0–4 | Ref | Ref | Ref |
5–9 | 1.40 (1.36, 1.44) | 1.60 (1.57, 1.63) | 1.12 (0.99, 1.27) |
10–14 | 1.94 (1.86, 2.01) | 2.19 (2.13, 2.25) | 1.56 (1.32, 1.85) |
≥15 | 2.63 (2.47, 2.80) | 2.77 (2.66, 2.89) | 1.70 (1.26, 2.28) |
Men | |||
Age (years) | |||
75–79 | Ref | Ref | – |
80–84 | 1.00 (0.92, 1.10) | 1.19 (1.13, 1.25) | |
85–89 | 0.79 (0.71, 0.89) | 1.25 (1.18, 1.33) | |
≥90 | 0.46 (0.37, 0.56) | 1.10 (1.01, 1.20) | |
Type of residential area | |||
Rural | Ref | Ref | |
Urban | 1.16 (1.07, 1.26) | 1.30 (1.24, 1.36) | |
Number of other drugs | |||
0–4 | Ref | Ref | |
5–9 | 2.05 (1.86, 2.25) | 2.15 (2.04, 2.26) | |
10–14 | 3.36 (2.99, 3.78) | 3.40 (3.19, 3.62) | |
≥15 | 5.61 (4.74, 6.64) | 5.07 (4.61, 5.58) |