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. Author manuscript; available in PMC: 2011 Feb 2.
Published in final edited form as: Circulation. 2010 Jan 18;121(4):529–536. doi: 10.1161/CIRCULATIONAHA.109.862946

Figure 5. Hearts of PGT targeted mice show chamber dilatation with normal interventricular septum thickness.

Figure 5

(a) Wild type mice (n = 3) have normal dimensions of the cardiac chambers (solid line). The interventricular septum, an indicator of intrinsic myocardial muscle development, is also normal (arrow).

(b) PGT Neo/Neo mouse (n = 3) shows dilated right and left ventricular chambers (lines), but the interventricular septum, an indicator of intrinsic heart muscle development, is normal (arrow).

(c) PGT −/− mouse (n = 3) shows finding similar to (b).