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. Author manuscript; available in PMC: 2010 Mar 11.
Published in final edited form as: Prog Biophys Mol Biol. 2009 Jan 30;98(2-3):161–170. doi: 10.1016/j.pbiomolbio.2009.01.010

Fig. 1.

Fig. 1

Diagram of the equivalent circuit components of our mathematical model of the human atrial myocyte action potential. (A) A schematic of the time- and voltage-gated membrane currents, ion pumps and exchangers, as well as the ligand-gated K+ current, IK(ACh), activated by muscarinic agonists. (B) I–V relationships of IK(ACh) corresponding to two different concentrations of either acetylcholine (ACh). (C) Steady-state activation (solid line) and inactivation (dashed line) relationships for INa in this model of the human atrial myocyte.