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. Author manuscript; available in PMC: 2010 Mar 11.

Published in final edited form as: Phys Med Biol. 2009 May 6;54(10):3083–3099. doi: 10.1088/0031-9155/54/10/008

Table 2.

% bias and % stddev at a single voxel in various tissue regions for 1000 noisy samples with LS estimation.

LS		% Bias	% Stddev
	k₁ (1/min)	1.97	21.4
Hypoxic Tumor	k₂ (1/min)	1.01	15.7
Hypoxic Tumor	k₃ (1/min)	0.97	13.5
	β	−1.13	27.9
	K_i (1/min)	0.19	6.30

	k₁ (1/min)	−2.92	11.5
Necrotic Tumor	k₂ (1/min)	−2.05	10.7
Necrotic Tumor	k₃ (1/min)	0.66	15.9
	β	28.2	81.8
	K_i (1/min)	−0.80	13.3

	k₁ (1/min)	1.74	20.1
Normoxic Tumor	k₂ (1/min)	1.10	14.9
Normoxic Tumor	k₃ (1/min)	0.56	42.9
	β	−1.04	28.2
	K_i (1/min)	−0.45	40.6

	k₁ (1/min)	−1.32	13.0
Normal Tissue	k₂ (1/min)	−0.91	10.3
Normal Tissue	k₃ (1/min)	0.79	35.0
	β	4.97	43.9
	Ki (1/min)	−0.65	32.6