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. Author manuscript; available in PMC: 2010 Mar 11.
Published in final edited form as: Phys Med Biol. 2009 May 6;54(10):3083–3099. doi: 10.1088/0031-9155/54/10/008

Table 5.

%bias at a single voxel centered in the hypoxic tumor region for −30% peak-amplitude shift and ±10sec peak-location shift in input function for LS estimation without any noise.

%Bias −30% Peak
Amplitude Shift
+10sec Peak
Location Shift
−10sec Peak
Location Shift
k1 (1/min) 15.7 −91.3 16.1
k2 (1/min) 42.4 −88.8 22.9
k3 (1/min) 18.8 25.8 2.8
β 53.0 105.3 21.4
Ki (1/min) 24.2 −17.1 −2.6