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%bias at a single voxel centered in the hypoxic tumor region for −30% peak-amplitude shift and ±10sec peak-location shift in input function for LS estimation without any noise.
| %Bias | −30% Peak Amplitude Shift |
+10sec Peak Location Shift |
−10sec Peak Location Shift |
|---|---|---|---|
| k1 (1/min) | 15.7 | −91.3 | 16.1 |
| k2 (1/min) | 42.4 | −88.8 | 22.9 |
| k3 (1/min) | 18.8 | 25.8 | 2.8 |
| β | 53.0 | 105.3 | 21.4 |
| Ki (1/min) | 24.2 | −17.1 | −2.6 |
